CHAPS study (compression hosiery for the prevention of post-thrombotic syndrome)

24 June 2021

​Imperial College London are looking for Principle Investigators and secondary care sites to recruit to the NIHR-HTA funded CHAPS study (compression hosiery for the prevention of post-thrombotic syndrome).

Imperial College London are currently conducting the CHAPS study, an NIHR-HTA funded RCT investigating the role of compression hosiery for the prevention of post-thrombotic syndrome in patients who have been diagnosed with their first, acute DVT. Participants will be randomised to either anticoagulation alone or anticoagulation in addition to compression stockings. The primary aim is to measure the difference in incidence of PTS at a median of 18 months follow up between the two treatment arms. This definitive trial will provide robust evidence regarding the effectiveness of compression stockings in the prevention of the post-thrombotic syndrome (PTS).

The study, led by Professor Alun Davies, is being conducted across a number of secondary care sites in the UK. The study recruitment has been affected by the COVID-19 pandemic. The team are now looking to identify additional secondary care sites to recruit to this NIHR portfolio study. Owing to the impact of COVID-19, the team fully understand that potential sites may not be able to proceed with set-up until the latter part of 2021 and are happy to commence discussions in the meantime.

Please do pass information about this opportunity onto colleagues within your Trust who manage patients with DVT.

For more information and to find out how you can be part of this important collaboration, please contact Sarrah Peerbux (Trial Manager) at s.peerbux@imperial.ac.uk, or chapstrial@imperial.ac.uk.

 

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